Microbial Profiling with dWMS Case Study

Renew Biotechnologies’ Direct Whole Methylome Sequencing (dWMS) platform delivers robust, PCR-free microbial profiling that combines species-level quantification with genome-wide methylation detection in a single, scalable workflow. Unlike conventional 16S-based methods constrained by PCR-induced bias, copy number variation, and poor primer coverage, dWMS enables taxonomic and epigenetic discovery directly from native DNA, even under low-input conditions. This case study demonstrates how dWMS outperforms targeted methods in species resolution, functional depth, and data fidelity, positioning it as a high-impact alternative for microbial community profiling and microbiome research.

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